Not 0 but O

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Catechol-o-methyltransferase inhibitor tolcapone improves learning and memory in naïve but not in haloperidol challenged rats

Objective(s): Dopamine plays an important role in cognitive functions. Inhibition of the dopamine-degrading enzyme catechol-O-methyltransferase (COMT) may have beneficial effects. Our aim was to assess the effect of COMT inhibitor tolcapone (TCP) on learning and memory in naïve and haloperidol-challenged rats.Materials and Methods: Male ...

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2 0 0 0 T O 2 0 0 6

Christopher H. Wheeler is a research officer in the Research division of the Bank. He previously was an assistant professor of economics at Tulane University in New Orleans. Wheeler received his doctoral and master’s degrees in economics from the University of Wisconsin-Madison in 1998 and 1995, respectively, and his bachelor’s degree in economics from Colby College in Waterville, Maine, in 199...

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LEWIS-BASE ADDUCTS OF LEAD(II) COMPOUNDS V,* SYNTHESIS AND STRUCTmAL CHARACTEREATION OF MONONUCLEAR (ACETATO-0,O') BIS(2,Zr-BIPYRIDINE) (PERCHLORATO-0,O') LEAD(II) AND BIS (2,Z'-BIPYRIDIW) BIS(PERCHL0RATO-0,O') LEAD(II)

The synthesis and single-crystal X-ray structure determination of the title compound [(bipy) , Pb(0 ,CMe) (O ClO )] (1) and [(bipy) Pb(ClO ) ] (2) is described. Compound (I) crystallizes in the triclinic space group P1(2), a= 7.384(2), b= 12.824(3), c= 10.622(6) A, ?= 73.41(2), ?= 80.98(2), ?= 73.68(2)', Z= 2, and R =0.033 for 3408 independent reflections .Compound (2) crystallizes in the ...

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ژورنال

عنوان ژورنال: Nature

سال: 1997

ISSN: 0028-0836,1476-4687

DOI: 10.1038/385384c0